NOD-like receptors (NLRs): bona fide intracellular microbial sensors
نویسندگان
چکیده
منابع مشابه
NOD-LIKE RECEPTORS (NLRs)
NLR Proteins In mammals, germ-line encoded pattern recognition receptors (PRRs) detect the presence of pathogens either directly through recognition of pathogen-associated molecular patterns (PAMPs) or indirectly through sensing host-derived danger signals (DAMPs). The innate immune system comprises several classes of PRRs that allow the early detection of pathogens at the site of infection. Th...
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ژورنال
عنوان ژورنال: Current Opinion in Immunology
سال: 2008
ISSN: 0952-7915
DOI: 10.1016/j.coi.2008.06.001